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Allele : Plxna4<tm1Matl> plexin A4; targeted mutation 1, Marc Tessier-Lavigne

Primary Identifier  MGI:3579185 Allele Type  Targeted
Attribute String  Null/knockout Gene  Plxna4
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A pgk-neomycin cassette with a 5' endoplasmic reticulum retention signal and a 3' myc epitope replaced exons 18-19, which encode the transmembrane domain. RT-PCR of mutants failed to detect transcript from 3' of the insertion in mutants. Northern blot failed to detect the truncated transcript from mutants.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • PLA4 KO,
  • PLA4 KO,
  • PlexinA4<->,
  • PlexinA4<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

26 Publication categories