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Allele : Arhgap6/Hccs/Mid1<tm1Hzo> Rho GTPase activating protein 6; targeted mutation 1, Huda Y Zoghbi

Primary Identifier  MGI:3580071 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Arhgap6
Transmission  Germline Strain of Origin  129S7/SvEvBrd
Is Recombinase  false Is Wild Type  false
molecularNote  The gene was replaced by a puromycin resistance gene and a loxP site in ES cells in which Arhgap6 had already been subjected to targeted mutation to replace exons 6, 7, and 8 with a neomycin resistance cassette and a loxP site. The two loxP sites are situated so that cre excision eliminates both resistance genes and all intervening DNA. All of Mid1, the entire Hccs gene, and all of Arhgap6 3' of exon 5 are thus conditionally deleted.
  • mutations:
  • Insertion
  • synonyms:
  • MLS<2loxP>,
  • MLS<2loxP>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories