Primary Identifier | MGI:3580423 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence, Modified isoform(s) | Gene | Axin1 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The coding sequence in exon 2 encoding the essential RGS domain was replaced by myc-tagged Axin1 cDNA. This cDNA sequence is for isoform 1, which is 36 amino acids shorter than isoform 2. The mutant protein was expressed at the same level as wild-type. |