| Primary Identifier | MGI:3580424 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Pyy |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exons 2-4, spanning amino acids 7-93, were replaced with an in-frame lacZ and a floxed PGK-neo selection cassette. The neo was removed via cre-mediated recombination. RT-PCR confirmed absence of transcript in colon samples from mutant mice. Betagalactosidase activity was detected in the colon and around the periphery of the islets. |