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Allele : Trp53<tm1Gev> transformation related protein 53; targeted mutation 1, Gerard I Evan

Primary Identifier  MGI:3582594 Allele Type  Targeted
Gene  Trp53 Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  The hormone-binding domain (encoding amino acids 281-599) of a modified estrogen receptor was fused in-frame at the 3' end of the coding sequence. Three new amino acids were introduced at the junction. A Floxed Neo cassette was inserted 580 bp down-stream from the polyadenylation site. The polyadenylation signal and other 3' untranslated sequences were left intact.
  • mutations:
  • Insertion
  • synonyms:
  • p53ER<TAM>,
  • p53ER<TAM>KI,
  • p53<ER>,
  • p53<KI>,
  • p53ER<TAM>,
  • p53<KI>,
  • p53<ER>,
  • p53ER<TAM>KI,
  • Trp53<KI>,
  • Trp53<KI>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

34 Publication categories