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Allele : Ntrk3<tm1Ddg> neurotrophic tyrosine kinase, receptor, type 3; targeted mutation 1, David D Ginty

Primary Identifier  MGI:3583736 Allele Type  Targeted
Attribute String  Not Specified Gene  Ntrk3
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A phenylalanine to alanine substitution mutation at residue 617 (F617A) was introduced via homologous recombination using a mutagenized construct with an FRT flanked neomycin resistance tag. Heterozygotes were bred with mice bearing Tg(ACTFLPe)9205Dym which expressed FLP1 recombinase. The resulting allele has the F617A mutation but the neomycin resistance cassette has been excised.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • TrkC<F617A>,
  • TrkC<F617A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories