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Allele : Gria3<tm2Rlh> glutamate receptor, ionotropic, AMPA3 (alpha 3); targeted mutation 2, Richard L Huganir

Primary Identifier	MGI:3584157	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Gria3
Transmission	Germline	Strain of Origin	(129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase	false	Is Wild Type	false

molecularNote

A targeting vector was designed to insert a neomycin resistance cassette in the exon encoding transmembranes 1 and 2. Western blot of mutant brain samples confirmed absence of protein.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Glur3<->,
Glur3<->

earliestPublication:
Gardner SM, et al. (2005) Calcium-permeable AMPA receptor plasticity is mediated by subunit-specific interactions with PICK1 and NSF. Neuron 45(6):903-15

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

5 Publication categories

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