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Allele : Cd19<tm1(cre)Thr> CD19 antigen; targeted mutation 1, Terence H Rabbitts

Primary Identifier  MGI:3584432 Allele Type  Targeted
Attribute String  Recombinase Gene  Cd19
Transmission  Germline Strain of Origin  129S/SvEv-Gpi1<c>
Is Recombinase  true Is Wild Type  false
molecularNote  In frame insertion of a cre recombinase gene into the first coding exon followed by an frt-flanked neomycin cassette. A frameshift mutation was also introduced into exon 5. This allele expresses cre recombinase specifically in B lineage cells throughout development. This allele was made using the same construct used for Cd19tm1(cre)Cgn, however CCB ES cells were used for targeting.
  • mutations:
  • Insertion
  • synonyms:
  • CD19-cre,
  • CD19-cre
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

10 Publication categories