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Allele : Mrtfb<Gt(RRJ478)Byg> myocardin related transcription factor B; gene trap RRJ478, BayGenomics

Primary Identifier  MGI:3587937 Allele Type  Gene trapped
Attribute String  Conditional ready, Null/knockout, Reporter Gene  Mrtfb
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A gene trap vector was inserted into intron 10, resulting in the production of a fusion protein encoded by the first 10 exons of MKL/myocardin-like 2 fused in-frame to a beta-galactosidase-neomycin phosphotransferase II reporter gene. Northern blot failed to detect transcript in mutants. A floxed splice acceptor site allows for recovery of transcription following cre-mediated recombination.
  • mutations:
  • Insertion of gene trap vector
  • synonyms:
  • MRTF-B<delta>,
  • MRTF-B<delta>,
  • Mkl2<Gt(pGT0Lxf)1Ucd>,
  • Mkl2<Gt(pGT0Lxf)1Ucd>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

7 Publication categories