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Allele : Arhgap1<tm1Yizh> Rho GTPase activating protein 1; targeted mutation 1, Yi Zheng

Primary Identifier	MGI:3606252	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Arhgap1
Transmission	Germline	Strain of Origin	129S6/SvEvTac
Is Recombinase	false	Is Wild Type	false

molecularNote

Part of exons 3 and 4, including the ATG, were replaced by the neomycin resistance gene. Immunoblot of mutant MEFs failed to detect protein.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
Cdc42GAP<->,
Cdc42GAP<->

earliestPublication:
Wang L, et al. (2005) Cdc42GAP regulates c-Jun N-terminal kinase (JNK)-mediated apoptosis and cell number during mammalian perinatal growth. Proc Natl Acad Sci U S A 102(38):13484-9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

9 Publication categories

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