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Allele : Spag16<tm1Jfs> sperm associated antigen 16; targeted mutation 1, Jerome F Strauss III

Primary Identifier  MGI:3606977 Allele Type  Targeted
Attribute String  Null/knockout Gene  Spag16
Transmission  Chimeric Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
description  Haploinsufficiency of Spag16 prevents genetic transmission of the mutated allele and generation of non-chimeric heterozygous mice. All phenotype data reported are from chimeric mice.
molecularNote  A targeting vector was designed to replace exon 11 with a PGK-neo selection cassette, preventing expression of the 35-kDA protein and the WD repeats of the 71-kDa protein.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories