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Allele : Dnmt3b<tm1Jae> DNA methyltransferase 3B; targeted mutation 1, Rudolf Jaenisch
Primary Identifier  MGI:3623148 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Dnmt3b
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a frt-flanked PGK-neo and a loxP site into intron 15 and a second loxP site into intron 19. The floxed exons encode the catalytic domains. The neo was removed via FLP mediated recombination. Western blot confirmed that this is a silent mutation.
  • mutations:
  • Insertion
  • synonyms:
  • Dnmt3b<2lox>,
  • Dnmt3b<2lox>,
  • Dnmt3b<L>,
  • Dnmt3b<L>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

14 Publication categories





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