|  Help  |  About  |  Contact Us

Allele : Dicer1<tm1Tara> dicer 1, ribonuclease type III; targeted mutation 1, Alexander Tarakhovsky

Primary Identifier  MGI:3622169 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Dicer1
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted to flank exon 22, which encodes the majority of the RNase III domain. Loss of this exon would result in the generation of in-frame stop codons generated by frameshift mutations, likely to destabilize the resulting transcript. Flp mediated recombination removed an FRT-flanked neo that was included in the vector.
  • mutations:
  • Insertion
  • synonyms:
  • Dicer<f>,
  • Dicer<f>,
  • Dicer<flox>,
  • Dicer<fl>,
  • Dicer<fl>,
  • Dicer<flox>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

35 Publication categories