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Allele : Gria2<tm2Rlh> glutamate receptor, ionotropic, AMPA2 (alpha 2); targeted mutation 2, Richard L Huganir

Primary Identifier  MGI:3623451 Allele Type  Targeted
Attribute String  Not Specified Gene  Gria2
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a floxed neo into the locus as well as the K882A substitution into the exon encoding transmembrane domain 4 and the C terminus region. The neo was subsequently removed via cre recombinase expression. A reduction in the levels of the long isoform was found particularly in mutants of 1 month of age.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • GluR2 K882A,
  • GluR2 K882A
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

8 Publication categories