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Allele : Nnt<G745D> nicotinamide nucleotide transhydrogenase; G745D

Primary Identifier  MGI:3625823 Allele Type  Chemically induced (ENU)
Gene  Nnt Strain of Origin  (C3H/HeH x BALB/c)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The mutation was identified as G>A substitution in exon 14, resulting in a nonconservative substitution of glycine by aspartic acid at amino acid 745 (p.G745D; p.G494D in exon 9 in the C57BL/6J strain (which has a 5-exon 251aa deletion)). Western blot analysis demonstrated that expressed protein was present in pancreatic islets of homozygous mice.
  • mutations:
  • Single point mutation
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories