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Allele : Rcan2<tm1Jmol> regulator of calcineurin 2; targeted mutation 1, Jeffery D Molkentin

Primary Identifier	MGI:3641543	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Rcan2
Transmission	Germline	Strain of Origin	129
Is Recombinase	false	Is Wild Type	false

molecularNote

Exons 2 and 3 were replaced with a neomycin resistance gene via homologous recombination. Wesetern blot confirmed absence of protein in mutant heart, skeletal muscle and brain.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
mcip2<->,
mcip2<->

earliestPublication:
Sanna B, et al. (2006) Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo. Proc Natl Acad Sci U S A 103(19):7327-32

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

4 Publication categories

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