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Allele : Mrtfa<tm1Eno> myocardin related transcription factor A; targeted mutation 1, Eric N Olson

Primary Identifier  MGI:3662669 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mrtfa
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A vector was designed to delete a part of exon 9 and all of exon 10, which encode the basic, glutamine-rich and SAP domains. A lacZ was fused in frame with exon 9 and a neo cassette. RT-PCR demonstrated that the correct exons were deleted and that exon 8 was spliced to exon 12, thereby deleting the lacZ-neo cassette. The resulting truncated protein would be nonfunctional.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • MRTFA<->,
  • MRTFA<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

27 Publication categories