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Allele : Igl<tm2.1Bgmn> immunoglobulin lambda chain complex; targeted mutation 2.1, Marianne Bruggemann

Primary Identifier	MGI:3701069	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Igl
Transmission	Germline	Strain of Origin	129P2/OlaHsd-Hprt1<b-m3>
Is Recombinase	false	Is Wild Type	false

molecularNote

LoxP insertions and cre-mediated recombination resulted in a 120Kb deletion spanning C1 through C2, and including C2 and C3.

mutations:
Deletion

cellLines:
Not Specified

synonyms:
1.3-2.4delta,
L<->,
L<->,
C1<->C2<->C3<->C4<->,
C1<->C2<->C3<->C4<->,
1.3-2.4delta

earliestPublication:
Zou X, et al. (2003) Block in development at the pre-B-II to immature B cell stage in mice without Ig kappa and Ig lambda light chain. J Immunol 170(3):1354-61

1 Feature

Genome

0 Expresses

12 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

7 Publication categories

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