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Allele : Lhx6<tm2Vpa> LIM homeobox protein 6; targeted mutation 2, Vassilis Pachnis

Primary Identifier  MGI:3702518 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lhx6
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2 through 4 and part of exon 5 were replaced with an IRES-eGFP and a floxed PGK-neo cassette. The neo cassette was then removed in vivo by Cre-mediated recombination. Immunohistochemistry and western blot analysis confirmed near total loss of protein expression in homozygous mice. No GFP expression is seen in heterozygotes.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Lhx6<tm2Pach>,
  • Lhx6<tm2Pach>,
  • Lhx6<->,
  • Lhx6<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories