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Allele : Cadps2<tm1Tfr> Ca2+-dependent activator protein for secretion 2; targeted mutation 1, Teiichi Furuichi

Primary Identifier	MGI:3707315	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Cadps2
Transmission	Germline	Strain of Origin	C57BL/6NSlc
Is Recombinase	false	Is Wild Type	false

molecularNote

Exon 1 was replaced by a pgk-neo cassette flanked by loxP sites. Western blot confirmed absence of protein in mutant cerebellum, neocortex and hippocampus.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

synonyms:
Caps2<->,
Caps2<->,
Caps2 KO,
Caps2 KO

earliestPublication:
Sadakata T, et al. (2007) Impaired cerebellar development and function in mice lacking CAPS2, a protein involved in neurotrophin release. J Neurosci 27(10):2472-82

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

19 Publication categories

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