Primary Identifier | MGI:3711412 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Sh3bp2 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to replace parts of exons 4 and 5 with a neomycin resistance cassette. These exons encode part of the PH domain. Western blot confirmed absence of protein in mutant splenic B Cells. |