|  Help  |  About  |  Contact Us

Allele : Trpm8<tm1Apat> transient receptor potential cation channel, subfamily M, member 8; targeted mutation 1, Ardem Patapoutian

Primary Identifier  MGI:3716558 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Trpm8
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Velocigene technology was used to delete sequences encoding amino acid residues 2-29 and insert a farnesylated enhanced GFP gene followed by an SV40polyA tail in frame with the start codon of the endogenous gene. RT-PCR confirmed absence of wild-type transcript in mutants, however, in some samples a truncated splice variant was detected at low levels.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Trpm8<EGFPf>,
  • Trpm8<EGFPf>,
  • Trpm8<->,
  • Trpm8<->
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

39 Publication categories