|  Help  |  About  |  Contact Us

Allele : Grem1<tm1Ecan> gremlin 1, DAN family BMP antagonist; targeted mutation 1, Ernesto Canalis

Primary Identifier  MGI:3761925 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Grem1
Transmission  Germline Strain of Origin  (129 x C57BL/6)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was placed 335 bp upstream of exon 2. A second loxP site along with a Frt-flanked PGK-neomycin selection cassette was placed within exon 2, 550 bp downstream of the stop codon and deleting the final 66 bp of the exon. Expression of the targeted locus was unchanged in homozygous mice as determined by quantitative PCR.
  • mutations:
  • Insertion
  • synonyms:
  • Grem1<flox>,
  • grem1<loxP>,
  • grem1<loxP>,
  • Grem1<flox>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

16 Publication categories