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Allele : Cdkn2b<tm2Brn> cyclin dependent kinase inhibitor 2B; targeted mutation 2, Anton Berns
Primary Identifier  MGI:3767459 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cdkn2b
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 1 and 2 were replaced with a PGK-hyg cassette with a 5' loxP site in ES cells containing the Cdkn2atm1.1Brn. Integration occurred on the chromosome that contained the wild-type Cdkn2atm1.1Brn allele. The absence of the p15Ink4b and p16Ink4a protein products was confirmed by western blot analysis on mouse embryonic fibroblasts.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Ink4ab<->,
  • Ink4ab<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories





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