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Allele : Pgr<tm3(rtTA2S*M2)Lyd> progesterone receptor; targeted mutation 3, John P Lydon

Primary Identifier  MGI:3768562 Allele Type  Targeted
Attribute String  Transactivator Gene  Pgr
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  An improved reverse tetracyclin-dependent transactivator (rtTA2S-M2) and a floxed neo cassette were inserted into exon 1. Expression of the transactivator is under the control of the endogenous promoter. Northern blot analysis was performed to confirmed expression of rtTA in mammary gland and uterus. The insertion also results in a null allele as stated by the authors.
  • mutations:
  • Insertion
  • synonyms:
  • PR<rtTA>,
  • PR<rtTA>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele