| Primary Identifier | MGI:3768659 | Allele Type | Targeted |
| Gene | Cd79b | Transmission | Germline |
| Strain of Origin | 129/Sv | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The cytoplasmic tail from amino acid position 183 to 228 was replaced with the cytoplasmic tail of Cd79a from amino acid position 161 to 220. A stop codon follows the last amino acid of the inserted Cd79a segment. A floxed neo cassette was inserted downstream of the Ig domain and subsequently removed by cre-mediated recombination. The presence of the modified protein and the absence of the full length endogenous transcript was confirmed by western blot analysis on B cell lysates. |
