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Allele : Spi1<tm3Dgt> Spi-1 proto-oncogene; targeted mutation 3, Daniel G Tenen

Primary Identifier  MGI:3773989 Allele Type  Targeted
Gene  Spi1 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  The endogenous gene was replaced with one in which the three Runx1 binding sites within a floxed upstream regulatory element (URE) were mutated from TGTGGT to TGACCT by sire-directed mutagenesis. A frt-flanked neo cassette was inserted upstream of the URE.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • PU.1-URE-mRunx,
  • PU.1-URE-mRunx,
  • mRunx1<ki>,
  • mRunx1<ki>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories