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Allele : Ldha<a-m7Neu> lactate dehydrogenase A; mutation 7, Neuherberg

Primary Identifier  MGI:3776295 Allele Type  Chemically induced (ENU)
Gene  Ldha Strain of Origin  (102/El x C3H/El)F1
Is Recombinase  false Is Wild Type  false
molecularNote  ENU-mutagenesis resulted in a transition at codon 194 (GAC to GCC) that caused an amino acid substitution of alanine for aspartic acid at position 194 (D194A). Enzyme activity is reduced to 63% of wild-type in heterozygotes and 24% of wild-type in ho0mozygotes.
  • mutations:
  • Single point mutation
  • synonyms:
  • Ldh1<7Neu>,
  • LDH 1962,
  • Ldh1<7Neu>,
  • Ldh1<a7Neu>,
  • Ldh1<a7Neu>,
  • LDH 1962
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories