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Allele : Tpp2<tm1.1Gnie> tripeptidyl peptidase II; targeted mutation 1.1, Gabriele Niedermann

Primary Identifier  MGI:3783750 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tpp2
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Evans Syndrome J:221205.
molecularNote  Exons 11 and 12 were removed by germ-line, cre-mediated recombination. The absence of protein activity was confirmed by an alanyl-alanyl-phenylalanyl-7-amino-4-methylcoumarin-degradation assay on splenocyte lysates and the absence of protein product was confirmed by western blot analysis on peripheral blood cell extracts.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • TPPII KO,
  • TPPII KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories