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Allele : Drosha<tm1Litt> drosha, ribonuclease type III; targeted mutation 1, Dan R Littman
Primary Identifier  MGI:3801076 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Drosha
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was used to introduce a loxP-flanked neomycin resistance cassette to intron 8, and an additional loxP site to intron 9 of the gene. The construct was electroporated into 129P2/OlaHsd-derived E14 embryonic stem (ES) cells. The neomycin cassette was excised with a C57BL/6 background EIIa-Cre, leaving loxP sites on either side of exon 9.
  • mutations:
  • Insertion
  • synonyms:
  • Drosha<lox>,
  • Drosha<flEx9>,
  • Drosha<F>,
  • Drosha<F>,
  • Drosha<flEx9>,
  • Drosha<lox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

28 Publication categories





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