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Allele : Dicer1<tm1Snj> dicer 1, ribonuclease type III; targeted mutation 1, Stephen N Jones

Primary Identifier	MGI:3809260	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Dicer1
Transmission	Germline	Strain of Origin	129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase	false	Is Wild Type	false

molecularNote

A floxed neo cassette was inserted upstream of exon 15 and an additional loxP site was inserted downstream of exon 17. Germ line, cre mediated recombination was used to remove the neo cassette.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Dicer<c>,
Dicer<c>

earliestPublication:
Mudhasani R, et al. (2008) Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells. J Cell Biol 181(7):1055-63

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

9 Publication categories

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