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Allele : Xiap<tm1Hs> X-linked inhibitor of apoptosis; targeted mutation Hermann Steller

Primary Identifier  MGI:3809790 Allele Type  Targeted
Gene  Xiap Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  The first two codons of the RING doman (C449 and K450) were replaced with STOP codons by homologous recombination. This mutation truncates the RING domain and the 13 amino acid sequence between the RING and C terminus. The frt-flanked neo cassette inserted into intron 2 was removed by germ line, flp mediated recombination.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • XIAP<deltaRING>,
  • XIAP<deltaRING>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

13 Publication categories