| Primary Identifier | MGI:3809761 | Allele Type | Targeted |
| Gene | Grm7 | Transmission | Germline |
| Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The last three codons in exon 10 comprising the C-terminal PDZ-ligand motif were replaced with alanine codons via homologous recombination. A floxed neo cassette was also inserted and subsequently removed by Cre mediated recombination in the ES cells. Western blot analysis indicated that protein levels were reduced by about 35% and 15% in the brains of homozygous and heterozygous mice, respectively. |
