| Primary Identifier | MGI:3810987 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Itm2b |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted 200 bp 5' of exon 2 and a floxed PGK-neo cassette was inserted in intron 2 via homologous recombination. The floxed PGK-neo cassette and exon 2 were deleted via in vivo Cre-mediated recombination. Western blot analysis of brain membranes from homozygous mice confirmed the absence of protein expression. |
