| Help | About | Contact Us

Allele : Trpm7<tm1.1Clph> transient receptor potential cation channel, subfamily M, member 7; targeted mutation 1.1, David E Clapham

Primary Identifier	MGI:3814706	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Trpm7
Transmission	Germline	Strain of Origin	129S4/SvJae
Is Recombinase	false	Is Wild Type	false

molecularNote

Cre mediated recombination of Trpm7^tm1Clph resulted in deletion of exon 17. Deletion of exon 17 removes the sequence preceding the first transmembrane domain and generates a frame shift mutation.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

earliestPublication:
Jin J, et al. (2008) Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis. Science 322(5902):756-60

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=74717490

MouseMine