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Allele : Batf3<tm1Kmm> basic leucine zipper transcription factor, ATF-like 3; targeted mutation 1, Kenneth M Murphy

Primary Identifier	MGI:3817232	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Batf3
Transmission	Germline	Strain of Origin	129S6/SvEvTac
Is Recombinase	false	Is Wild Type	false

molecularNote

Exons 1-2 were replaced by a floxed neomycin cassette. Cre-mediated recombination removed the neo cassette. Gene inactivation was confirmed by a lack of protein detected by immunoblot analysis of Th1 CD4⁺ T cells.

mutations:
Intragenic deletion,
Insertion

cellLines:
Not Specified

earliestPublication:
Hildner K, et al. (2008) Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity. Science 322(5904):1097-100

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

6 Carried By

0 Driven By

262 Publication categories

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