| Primary Identifier | MGI:3817874 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Cdx1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A retinoic acid response element (RARE) lies about 1-kb upstream from the coding sequence of the gene. The response element was replaced by a floxed neo cassette. Chimeric males bearing the targeted allele were crossed with transgenic mice expressing cre-recombinase to remove the neo-cassette. Whole-mount in situ hybridization revealed reduced expression of the gene locus during embryonic development including in the primitive streak phase and during formation of the neuroectoderm. |
