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Allele : Cnn2<tm1.2Jin> calponin 2; targeted mutation 1.2, Jian-Ping Jin
Primary Identifier  MGI:3820423 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cnn2
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted in introns 1 and 2 an an frt flanked neomycin resistance cassette was inserted downstream of the loxP site in intron 2. Mice were then crossed to Gt(ROSA)26Sor to produce mice with germline deletion of the frt flanked neomycin resistance cassette. These floxed mice (Cnn2tm1.1Jin) were then crossed with Tg(Zp3-cre)93Knw mice. Cre expression results in the germline excision of exon 2. These mice produce no protein product.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

9 Publication categories





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