Primary Identifier | MGI:3823041 | Allele Type | Targeted |
Gene | Htr2c | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 5 was replaced with one in which 5 adenosines were converted to guanosines by nucleotide substitutions giving rise to I156V, N158G and I160V amino acid substitutions. A floxed neo cassette was inserted upstream of exon 5 for selection purposes. Mice only express the isoform carrying these substitutions. |