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Allele : Htr2c<tm1Knk> 5-hydroxytryptamine (serotonin) receptor 2C; targeted mutation 1, Kazuko Nishikura

Primary Identifier  MGI:3823041 Allele Type  Targeted
Gene  Htr2c Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 5 was replaced with one in which 5 adenosines were converted to guanosines by nucleotide substitutions giving rise to I156V, N158G and I160V amino acid substitutions. A floxed neo cassette was inserted upstream of exon 5 for selection purposes. Mice only express the isoform carrying these substitutions.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • 5-HT2CR-VGV,
  • 5-HT2CR-VGV
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

7 Publication categories