Primary Identifier | MGI:3823246 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Lama5 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to flox exons 15-21, which encodes 40% of domain V that consists of laminin EGF-like repeats. Unlike Lama5tm2Jhm, the frt-flanked neo cassette inserted downstream of exon 21 was retained and leads to an alternate transcript involving the splicing of exon 20 to exon 22. |