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Allele : Mep1a<tm1Bond> meprin 1 alpha; targeted mutation 1, Judith S Bond

Primary Identifier  MGI:3833886 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mep1a
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette with an in-frame stop codon was inserted into the zinc-catalytic center encoded by exon 7. In the process, 140 bp were deleted at the targeting site. End-point PCR of kidney mRNA demonstrated the absence of transcription. Absence of protein product was indicated by immunoblot analysis of urine.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

17 Publication categories