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Allele : Axin1<tm4Cos> axin 1; targeted mutation 4, Frank Costantini

Primary Identifier  MGI:3840238 Allele Type  Targeted
Attribute String  Inserted expressed sequence Gene  Axin1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced with a myc-tagged cDNA lacking the six C-terminal amino acids followed by a floxed neo cassette. Germ line, cre mediated recombination was used to remove the neo cassette. Western blot confirmed that protein expression was reduced 3- to 4-fold compared to in wild-type mice.
  • mutations:
  • Insertion
  • synonyms:
  • Axin<deltaC6>,
  • Axin<deltaC6>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories