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Allele : Fto<tm1Urt> FTO alpha-ketoglutarate dependent dioxygenase; targeted mutation 1, Ulrich Ruther

Primary Identifier  MGI:3841156 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fto
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 2 and 3 were replaced with a neomycin resistance cassette. Immunohistochemistry failed to detect protein in the brown adipose tissue, pancreas, liver or stomach of homozygote mice. Expression of the nearby Rpgrip1l gene (Ftm) is unaffected as determined by RT-PCR of hypothalamus, liver, and adipose tissue.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

11 Publication categories