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Allele : Htr2c<tm1Jke> 5-hydroxytryptamine (serotonin) receptor 2C; targeted mutation 1, Joel K Elmquist

Primary Identifier  MGI:3841486 Allele Type  Targeted
Attribute String  Conditional ready, Null/knockout Gene  Htr2c
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed transcription blocker cassette (loxTB) was inserted between exons 3 and 4. Expression is disrupted unless reactivated by cre mediated recombination. The absence of transcript expression was confirmed by RT-PCR on cerebral cortex, whole hypothalamus, arcuate nucleus of the hypothalamus, and brainstem extracts.
  • mutations:
  • Insertion
  • synonyms:
  • 2C null,
  • 2C null,
  • loxTB 5-HT2CR,
  • loxTB 5-HT2CR
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

17 Publication categories