| Primary Identifier | MGI:3843498 | Allele Type | Transgenic |
| Attribute String | Recombinase | Gene | Tg(Hspa2-cre)1Eddy |
| Strain of Origin | C57BL/6 | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | The Hspa2-Cre transgene was designed with (from 5' to 3') a 53 bp mouse Acrv1 (acrosomal vesicle protein 1 [SP-10]) insulator element, a promoter element from the mouse Hspa2 locus (heat shock protein 2 [Hsp70-2]); containing the ATG start site and 892 bp of immediately upstream sequence), a 275 bp fragment of the cre gene, the bovine growth hormone 3' UTR and polyA sequence, and another 53 bp mouse Acrv1 insulator element. This transgene was injected into C57BL/6 pronuclear stage embryos. Expression of Cre recombinase is directed to the developing male germ cells. |
