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Allele : Arl8b<Gt(AK0793)Wtsi> ADP-ribosylation factor-like 8B; gene trap AK0793, Wellcome Trust Sanger Institute

Primary Identifier	MGI:3852843	Allele Type	Gene trapped
Attribute String	Null/knockout	Gene	Arl8b
Transmission	Germline	Strain of Origin	129P2/OlaHsd
Is Recombinase	false	Is Wild Type	false
Project Collection	Sanger Inst. Gene Trap Res.

molecularNote

A gene trap vector inserted into intron 1. Western blot analysis confirmed the absence of protein expression in homozygous embryos at E8.5.

mutations:
Insertion of gene trap vector

cellLines:
AK0793

earliestPublication:
Oka M, et al. (2017) Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos. J Cell Sci 130(20):3568-3577

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

6 Publication categories

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