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Allele : Dcp2<Gt(RRE061)Byg> decapping mRNA 2; gene trap RRE061, BayGenomics

Primary Identifier  MGI:4127248 Allele Type  Gene trapped
Attribute String  Hypomorph Gene  Dcp2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The gene trap vector insertion site was mapped to nucleotide 12535 within intron 1 of the Dcp2 gene. Western analysis of several organs from 4-week-old wild-type (WT) and homozygous littermates revealed the mice containing a homozygous insertion of the gene trap vector were not completely devoid of Dcp2 expression and were instead phenotypically hypomorphic with reduced protein expression in the different tissues that Dcp2 can normally be detected.
  • mutations:
  • Insertion of gene trap vector
  • synonyms:
  • Dcp2<beta>,
  • Dcp2<beta>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories