|  Help  |  About  |  Contact Us

Allele : Dtx1<tm1.2Mzl> deltex 1, E3 ubiquitin ligase; targeted mutation 1.2, Ming-Zong Lai

Primary Identifier  MGI:4355029 Allele Type  Targeted
Attribute String  Null/knockout Gene  Dtx1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A Frt-flanked neomycin cassette and a loxP site were placed downstream of exon 3. An additional loxP site was placed upstream of exon 3. Exon 3 and the neomycin cassette were deleted from the germline by crossing founder mice with cre-transgenic mice. Protein was undetectable in homozygote splenic lymphocytes as determined by immunoblot analysis.
  • mutations:
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories