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Allele : Themis<5AT161> thymocyte selection associated; 5AT161

Primary Identifier  MGI:4353412 Allele Type  Chemically induced (ENU)
Gene  Themis Inheritance Mode  Recessive
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  A T-to-A transversion generated a stop codon in place of the sequence encoding a tyrosine residue at position 489. Immunoblot analysis on homozygote thymus extracts detected only a very small amount of truncated protein, and mRNA levels in these extracts were one-third of endogenous levels.
  • mutations:
  • Single point mutation
  • synonyms:
  • Themis(Y489X),
  • Themis(Y489X)
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories