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Allele : Hnrnpk<tm1(KOMP)Wtsi> heterogeneous nuclear ribonucleoprotein K; targeted mutation 1, Wellcome Trust Sanger Institute

Primary Identifier  MGI:4363684 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Hnrnpk
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-CSD
description  Cell line EPD0323_2_B02 was successfully used to make chimeric mice. Germline transmission was accomplished. J:225947
molecularNote  The insertion of the L1L2_Bact_P cassette created a deletion of size 3186 starting at position 58544639 and ending at position 58547825 of Chromosome 13 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories